Plant Transcription Factor Database
Previous version: v3.0
Oryza sativa subsp. japonica
NF-YA Family
Species TF ID Description
LOC_Os02g53620.1NF-YA family protein
LOC_Os03g07880.1NF-YA family protein
LOC_Os03g07880.2NF-YA family protein
LOC_Os03g07880.3NF-YA family protein
LOC_Os03g29760.1NF-YA family protein
LOC_Os03g29760.2NF-YA family protein
LOC_Os03g29760.3NF-YA family protein
LOC_Os03g44540.1NF-YA family protein
LOC_Os03g48970.1NF-YA family protein
LOC_Os03g48970.2NF-YA family protein
LOC_Os03g48970.3NF-YA family protein
LOC_Os03g48970.4NF-YA family protein
LOC_Os07g06470.1NF-YA family protein
LOC_Os07g06470.2NF-YA family protein
LOC_Os07g41720.1NF-YA family protein
LOC_Os07g41720.2NF-YA family protein
LOC_Os08g09690.1NF-YA family protein
LOC_Os08g09690.2NF-YA family protein
LOC_Os10g25850.1NF-YA family protein
LOC_Os12g41880.1NF-YA family protein
LOC_Os12g41880.2NF-YA family protein
LOC_Os12g42400.1NF-YA family protein
LOC_Os12g42400.2NF-YA family protein
LOC_Os12g42400.3NF-YA family protein
LOC_Os12g42400.4NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982